Saizen 3.33mg HGH Injection

Saizen 3.33mg HGH Injection

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Saizen 3.33mg Injection HGH

Saizen 10 Iu Inj





Saizen 3.33mg HGH Injection [somatropin (rDNA origin) injection] is a human growth hormone produced by recombinant DNA technology. Saizen has 191 amino acid residues and a molecular weight of 22,125 daltons. Its amino acid sequence and structure are identical to the dominant form of human pituitary growth hormone. Saizen is available in 5 mg and 8.8 mg vials. The quantitative composition per vial is as follows:

5 mg (approximately 15 IU) vial: Each vial contains 5.0 mg somatropin (approximately 15 IU), 34.2 mg sucrose and 1.16 mg O-phosphoric acid.
8.8 mg (approximately 26.4 IU) vial: Each vial contains 8.8 mg somatropin (approximately 26.4 IU), 60.2 mg sucrose and 2.05 mg O-phosphoric acid. The pH is adjusted with sodium hydroxide or Ophosphoric acid


Pediatric Patients:

Saizen 3.33mg HGH Injection [somatropin (rDNA origin) injection] is indicated for the long-term treatment of children with growth failure due to inadequate secretion of endogenous growth hormone
1. Adult Onset: Patients who have growth hormone deficiency either alone, or associated with multiple hormone deficiencies (hypopituitarism), as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma; or

2. Childhood Onset: Patients who were growth hormone deficient during childhood who have growth hormone deficiency confirmed as an adult before replacement therapy with Saizen is started.


How should I use this medication?
The recommended dose depends on the circumstances and body weight of the person being treated. Your doctor will determine the appropriate dose of saizen to be injected.

Saizen is administered by injection only. It is usually injected subcutaneously (under the skin), although it can be given intramuscular (into the muscle) if your doctor prefers. If it is injected under the skin, it is important to rotate the site of injection in order to minimize the risk of fat wasting at the site of injection.

If you are using this medication at home, your doctor will ensure that you understand exactly how to use it. Make sure you ask any and all questions necessary to ensure that you use it exactly as prescribed. Please refer to the appropriate package insert for details on how to mix the medicine and for proper injection procedures. It is important to visit your doctor regularly during therapy to ensure that the medication is working safely and effectively.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose of the medicine, call your doctor for further instructions. Do not take a double dose to make up for a missed one.

Follow the package instructions for storing the medication. Do not use the solutions if they are discolored or contain particles.
Keep this medication out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication
Saizen 3.33mg HGH Injection injection should not be used by or given to anyone who:

is allergic to saizen or any ingredients of the medication

is a child with closed epiphyses (growth plates)

has active cancer

has a brain tumour

has an acute illness due to complications of surgery, has respiratory (breathing) failure, or has just had a serious accident

has certain types of eye damage due to diabetes (proliferative or preproliferative diabetic retinopathy)

has Prader-Willi syndrome and is severely obese or has severe breathing problems

What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

carpal tunnel syndrome

growth of birthmarks

joint pain

muscle pain

redness, pain, or swelling at site of injection

stiffness in the arms or legs

swelling of hands, feet, or lower legs

unusual tiredness or weakness

Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

depression of skin at place of injection

ear infection or other ear problems (in Turner’s syndrome)



nausea and vomiting

pain in hip or knee

skin rash or itching

severe abdominal pain, particulary in children

skin rash or itching

symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)

Stop taking the medication and seek immediate medical attention if any of the following occur:

severe or frequent headaches with nausea and vomiting or vision problems

signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.


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